Representation
How can a model learn useful features of biological sequence?
Investigate representations that retain information relevant to a defined biological task, with evaluation beyond the data used to develop the model.
Research / Genomics
Exploring how AI can connect patterns in genomic data with hypotheses about biological function.
Sequence, variation, and molecular activity offer different views of biology. Our research direction explores how models can connect those views without losing sight of the quality, provenance, and limitations of the underlying data.
Questions guiding this frontier
Representation
Investigate representations that retain information relevant to a defined biological task, with evaluation beyond the data used to develop the model.
Context
Explore connections between sequence variation and biological context. Treat an association as a starting point for investigation, not as proof of mechanism.
Prioritization
Study how uncertainty-aware models could help focus experimental attention on questions that are both meaningful and tractable.
The standard of evidence
A model’s output is not a clinical interpretation. Genomic predictions need appropriate validation, and research using human data requires suitable consent, governance, and privacy protections.
Bring a scientific challenge. Let’s explore what becomes possible when disciplines work together.
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